is a unit made up of three nucleotides that correspond to the three bases of the codon on the m RNA.
Each t RNA contains a distinct anticodon triplet sequence that can base-pair to one or more codons for an amino acid.
The Protein Data Bank (PDB) codes for the structural models used as end points of the animation are given. Once translation initiation is complete, the first aminoacyl t RNA is located in the P/P site, ready for the elongation cycle described below.
Both t RNAs are modeled as phenylalanine-specific t RNA from Escherichia coli, with the A/T t RNA as a homology model of the deposited coordinates. In addition, the ribosome has two other sites for t RNA binding that are used during m RNA decoding or during the initiation of protein synthesis. During translation elongation, t RNA first binds to the ribosome as part of a complex with elongation factor Tu (EF-Tu) or its eukaryotic (e EF-1) or archaeal counterpart.
For example, Helicobacter pylori has glutaminyl t RNA synthetase missing.